Variance Components Linkage Analysis with Repeated Measurements

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چکیده

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Variance components linkage analysis with repeated measurements.

BACKGROUND When subjects are measured multiple times, linkage analysis needs to appropriately model these repeated measures. A number of methods have been proposed to model repeated measures in linkage analysis. Here, we focus on assessing the impact of repeated measures on the power and cost of a linkage study. METHODS We describe three alternative extensions of the variance components appro...

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ژورنال

عنوان ژورنال: Human Heredity

سال: 2008

ISSN: 0001-5652,1423-0062

DOI: 10.1159/000194977